Endocrine Abstracts

Introduction: Papillary thyroid carcinoma (PTC) is a common thyroid gland malignancy. Postoperative suppression therapy with levothyroxine (LT4) is commonly used to prevent recurrence or progression of the disease. The optimal duration and dose of LT4 suppression therapy remain a matter of debate. The optimal duration and dose of LT4 suppression therapy remain a matter of debate, with recommendations varying based on the patient’s age, sex, tumor characteristics, and risk...

Background and aims: A growing number of studies show the impact of vitamin D deficiency on chronic diseases, such as obesity, type 2 diabetes, cardiovascular disorders etc. Recently the lower limit of vitamin D sufficiency, appeared to be safe and sufficient for skeletal health in the healthy general population, was documented as 20 ng/ml (50 nmol/l). The aim of current work is to evaluate whether the 25-OH vitamin D status is associated with the glucose control in type ...

Background: Diabetes is the most prevalent chronic metabolic disorder in children and adolescents, and incidence rates for both type-1 and type-2 diabetes are increasing worldwide. In recent years, the number of patients with type 1 diabetes is increasing mainly due to children under 5-years-old.Objective: To study the epidemiological indicators of T1DM among children of the Republic of Armenia (RA) from 2007 to 2016. Methods: Retrospective analysis of t...

Type 1 diabetes mellitus (T1DM) is one of the most frequent autoimmune disorders in childhood, adolescence and youth, developing due to autoimmune destruction of pancreatic β-cells, which leads to an absolute insulin deficiency. Gut microbiota (GM) is associated with the functions of the body’s immune system, and immune-mediated diseases, including T1DM. However, the exact mechanisms by which GM is involved in the T1DM are still unknown. Accumulating data suggest tha...

Introduction: Incidence of type 1 diabetes mellitus (T1DM) is rising steadily around the globe, including Armenia. It is one of the most common autoimmune and metabolic disorders in pediatric population, resulting from autoimmune destruction of pancreatic β-cells leading to insulin deficiency. Gut microbiota (GM) is reportedly involved in the pathogenesis of T1DM likely by influencing the immune response with the help of arginine-metabolizing enzymes. Arginase i...